|
|
|
 
   
   
USA
Tel: +1-800-615-0418
Fax: +1-703-722-0731
   

Data & Publications

Science of the Nanotrap®

The patented Ceres Nanotrap® is a carbon-based capture-particle that can be as small as 100 nm, comprising a molecular sieve portion; and an analyte binding portion; which further comprise a cross-linked region having modified porosity, comprising pore dimensions sufficient to exclude molecules larger than about 60 kDa. These particles enhance purification and diagnostic methods, including the harvesting of biomarkers.





Review Science of High Sensitivity Lyme Antigen Test using Nanotrap:

"The use of hydrogel microparticles to sequester and concentrate bacterial antigens in a urine test for Lyme disease" (Biomaterials, 2010 )    view report


Review Early Detection of Cancer Biomarkers using Nanotrap:

"Investigation of the Ovarian and Prostate Cancer Peptidome for Candidate Early Detection Markers Using a Novel Nanoparticle Biomarker Capture Technology" (AAPS Journal, 2010 )    view report


Review novel approach to ovarian cancer biomarker discovery using Nanotrap® technology:

"Covalent incorporation of a new class of dye based affinity baits in sieving hydrogel nanoparticles overcome roadblocks to cancer biomarker discovery" (Poster presented at 2010 AACR Conference )    view poster


Review novel approach to ovarian cancer biomarker discovery using Nanotrap® technology:

"A novel technological approach for the discovery of low molecular weight serum biomarkers based on ?smart? hydrogel nanoparticles applied to ovarian cancer" (Poster presented at 2009 AACR Conference)    view poster


Understand the Science of the Nanotrap® through a report published in NanoLetters:

"Smart Hydrogel Particles: Biomarker Harvesting: One-Step Affinity Purification, Size Exclusion, and Protection against Degradation" (NanoLetters, 2008, Vol. 8, No. 1)    view report


Publication in Nano Reserach highlights Nanotrap®'s capability as reliable test for trace amounts of HGH in urine:

"Concentration and preservation of very low abundance biomarkers in urine, such as human growth hormone (hGH), by Cibacron Blue F3G-A loaded hydrogel particles", Nano Research, 2008, 1(6): 502-518    view report


Publication in PLoS ONE presents Nanotrap®'s capabilties as harvesting and amplification tool:

"Core-Shell Hydrogel Particles Harvest, Concentrate and Preserve Labile Low Abundance Biomarkers", PLoS ONE, 3/10/2009   
view report


 

Ceres Nanosciences, Inc © 2011, All Rights Reserved