PRODUCT DESCRIPTION

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• Nanotrap® Magnetic Virus Particles demonstrated to capture and concentrate a wide range of viruses, including: influenza A (1), influenza B (1), respiratory syncytial virus (1), coronavirus 229E (1), coronavirus OC43 (2), SARS-CoV-2 (3)(4), Zika (10), chikungunya (10), pepper mild mottle virus (12), hepatitis A virus (16), and monkeypox (17).

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• Methods developed for clinical swab samples, saliva, wastewater, and blackwater. (3)(4)(7)(8)(13)(15)

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• Eliminate false negatives. Nanotrap® particles enabled the identification of SARS-CoV-2 RNA in 9 out of 32 diagnostic remnant samples that had previously tested negative for the virus. (4)

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• Increase assay sensitivity by capturing and concentrating low abundance viruses. Nanotrap® particles improved real-time RT-PCR signal in low viral load diagnostic remnant samples by an average of 3.1 Ct values and sequencing coverage in low viral load diagnostic remnant samples by 20-80%. (4)(14)

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• Successfully utilized in high-complexity and point-of-care RT-PCR assays with FDA Emergency Use Authorization for COVID-19. (9)(11)(13)

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• Nanotrap® particles utilize affinity capture and enrichment to attract and bind low abundance viruses. Nanotrap® particles do not utilize antibodies or other biomolecules as affinity molecules.​

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• Enables an automated method for concentrating and processing virus from 24 raw wastewater samples in 40 minutes, reducing processing time by at least 20-fold, as compared to other methods. (8)

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• Wastewater processing protocols available for manual or automated workflows that are used in dozens of leading wastewater testing labs.

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• Combine with Nanotrap® Enhancement Reagent to improve Ct values by at least 1-2 in your wastewater samples.

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• For Research Use Only. Not for use in diagnostic procedures.

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