App Note: Rapid SARS-CoV-2 RNA Extraction from Saliva Samples

Updated: Dec 7, 2020


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Key Advantages

> Nanotrap® Magnetic Virus Particles enable RNA extraction of viral RNA from saliva samples in just 20 minutes, and improve detection by 2-3 Ct values as compared to a

Proteinase K method recently described by a team from Yale University.


Technologies that enable rapid and sensitive detection of viral RNA from easy-to-collect samples, such as saliva, are in high demand. Nanotrap® Virus Particles capture and concentrate multiple strains of influenza, RSV, and coronavirus, thus enhancing detection of those viruses, even in co-infection scenarios.1-4 Here, we show that Nanotrap® Magnetic Virus Particles can capture and concentrate heat-inactivated SARSCoV- 2 from saliva samples that simulate patient samples. These results suggest that using Nanotrap® particles can improve sensitivity of saliva-based testing for SARS-CoV-2



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