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Wastewater-based Epidemiology

Nanotrap® Microbiome Particles rapidly concentrate microbes from raw sewage, requiring no filtration, centrifugation, or bead-beating.

Large-scale wastewater surveillance can be used to help communities monitor infection dynamics for SARS-CoV-2 and other microbes of concern. Robust, high-throughput methods based on Nanotrap Microbiome Particles are enabling wide-spread implementation.

A method using Nanotrap Microbiome A Particles was shown to detect 1 asymptomatic individual in a building of 415 residents and enabled early detection of nearly 85% of individual COVID-19 cases on a university campus.

Wastewater-based epidemiology workflow

Simplified workflow.

  • Eliminate filtration, centrifugation and bead beating methods, without sacrificing sensitivity.

  • Decrease overall fume hood time

Highly compatible.

Capture more. Get better data.

  • Improved capture efficiency with 2-10x higher recovery.

  • Even better results – Add a Nanotrap Enhancement Reagent to improve results by another 1-2 Ct values.

Environmentally friendly.
Less plastics = Less waste.


  • Decreased biohazard waste due to minimized plastics use compared to other methods.

  • Increased available lab storage space.

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Wastewater-based Epidemiology QuickStart Guide

What’s in the Guide?

  • Step-by-step workflow overview

  • Quick-start tips for each step in the workflow

  • Information on how to optimize your capture and concentration process to improve results and throughput, and more…

Poster-App Notes
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