Wastewater-based Epidemiology
Nanotrap® Microbiome Particles rapidly concentrate microbes from raw sewage, requiring no filtration, centrifugation, or bead-beating.
Large-scale wastewater surveillance is used to help communities monitor infection dynamics for viruses like SARS-CoV-2, bacteria, fungi, and parasites. Nanotrap Particle Technology is used by labs around the world to capture and concentrate important pathogens of interest.
A method using Nanotrap Microbiome A Particles was shown to detect 1 asymptomatic individual in a building of 415 residents and enabled early detection of nearly 85% of individual COVID-19 cases on a university campus.
Wastewater-based epidemiology workflow
Simplified workflow
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Eliminate filtration, centrifugation and bead beating methods, without sacrificing sensitivity.
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Spend less time in the fume hood.
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Shelf stable product for up to 6 years at room temperature — no need for cold storage.
Highly compatible
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Compatible with RT-qPCR, RT-ddPCR, RT-dPCR, and sequencing-based analysis methods.
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Manual and automated protocols available for use with a wide range of RNA extraction kits.
Get better data
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Improved capture efficiency with 2-10x higher recovery.
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Need greater performance? Add a Nanotrap Enhancement Reagent to improve results by another 1-2 Ct values.
Environmentally friendly
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Reduce biohazard waste
by using less plastic consumables compared
to other methods. -
Free up valuable lab storage space.
Supported by the U.S. National Institutes of Health.
Webinars and Interviews
Webinars
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LabRoots Webinar: Wastewater Surveillance: Expanding Microbes of Interest Monitoring Beyond SARS-CoV-2
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Labroots Webinar: Deploying SARS-CoV-2 wastewater monitoring in Kansas. A case study and adoption of high-throughput, automated sample processing
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MACHEREY-NAGEL Webinar: Case Studies in Wastewater Surveillance - Successful Testing Methods in Practice
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Labroots Webinar: Sample collection and concentration methods -- impact on wastewater-based surveillance for multi-pathogen panels
Helpful workflow videos
Interviews
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Interview with Nevada State Public Health Laboratory: How Nanotrap® Particle Technology is Improving the Public Health Response to SARS-CoV-2
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Interview with University of Massachusetts, Amherst: How Nanotrap® Technology for Wastewater Surveillance Improves SARS-CoV-2 Workflows
Poster & applications related to wastewater-based epidemiology testing
Application Notes
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Capture and Concentrate Microbes that Cause Sexually Transmitted Infections from Wastewater
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Capture and Concentrate Pathogenic Legionella Species from Environmental Water Samples
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Nanotrap Microbiome A and B Particles can be combined to improve microbe capture from wastewater
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Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission
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Comparison of Nanotrap Microbiome A Particles, membrane filtration, and skim milk workflows for SARS-CoV-2 concentration in wastewater
