Nanotrap Technology
About the Innovative Nanotrap Technology
Nanotrap® Particles are hydrogel particles, functionalized with chemical affinity baits that have very high affinities for different classes of analytes, such as proteins, peptides, nucleic acids, microbes, hormones, drugs-of-abuse, and extracellular vesicles.
The unique hydrogel structure facilitates rapid exchange with the sample for rapid binding. Nanotrap particles are magnetically functionalized, allowing for easy recovery from the sample. This process can be automated, enabling high-throughput sample processing.
The technology platform is well-validated, with over 80 publications and preprints and 14 patents to date.The technology platform is well-validated, with over 80 publications and preprints and 14 patents to date.
Nanotrap Particle Technology
Hydrogel particles facilitate rapid binding and removal of interfering substances, enabling analyte capture, concentration, and purification.
Hydrogel particles are highly versatile, with demonstrated functionality across sample types and volumes, ranging from small-volume plasma samples to large-volume wastewater samples.
Well-characterized affinity baits capture and concentrate multiple analytes from a type and size of the sample, unlocking access to multiplex and multi-omic testing modalities.
Magnetic and automation-ready, ideal for high-volume workflows or point-of-care devices
Room temperature stable for >6 years, providing cost-effective durability in a wide range of global settings
Ceres offers a range of Nanotrap® particle technologies designed to support different sample types, targets, and downstream applications. From protein and biomarker enrichment to microbial concentration and circulating cell-free DNA workflows, each Nanotrap particle platform is optimized for specific research and diagnostic needs.
Nanotrap® PEAK
Reveal more of the proteome. Dynamic range compression and protein enrichment for deeper, more reproducible mass spectrometry.
Nanotrap® NEAT
Reveal more molecular information. High-performance nucleic acid capture and purification for liquid biopsy and demanding biological samples.
Nanotrap® MICROBIOME
Reveal more microbial signal. Pathogen and nucleic acid concentration for infectious disease detection and surveillance.
Workflow Integration
The Nanotrap Platform can be integrated seamlessly into research and clinical workflows. The technology has been verified on automated platforms for high-throughput sample processing and integrated into point-of-care devices.
