Technology

Common barriers to effective clinical diagnostics

and research include:

  • Low concentration of analytes

  • Rapid degradation of analytes

  • Presence of interfering substances

  • Invasive sample collection requirements

The Nanotrap® particle technology overcomes these barriers, enabling the capture, concentration, and preservation of low abundance analytes from complex biological samples. 

 

A well validated technology platform with over 30 peer-reviewed publications and 14 patents to-date.

Nanotrap® particles are highly porous hydrogel particles, functionalized with chemical affinity baits which have very high affinities for different classes of analytes, such as proteins, peptides, nucleic acids, hormones, drugs of abuse, extracellular vesicles, and pathogens.

  • Proven sample inputs: CSF, serum, plasma, blood, cell culture, transport media, urine, oral fluid, and sweat

  • Wide range of sample volume: 25 µL to 40 mL

  • Versatile technology platform that is amendable to magnetic functionalization and lyophilization

  • Scalable from low to high-throughput laboratory needs

 
 

Workflow integration:  The Nanotrap platform can be integrated seamlessly into research and clinical workflows. There are magnetic versions of the Nanotrap particles that have been validated on automation platforms for high-volume sample processing workflows.

 

The proof is in the data

"Ceres’ Nanotrap Particles have outperformed the numerous depletion methods we have tried – we are obtaining confident identifications on lower level plasma proteins that required offline fraction to identify in the past. We are excited to be working in plasma again using this enabling technology!”

 

Kirk Hansen, Ph.D.

Director of the University of Colorado,    

School of Medicine, Proteomics Facility

"I cut my sample prep time by 4+ hours using Ceres' Nanotrap on-particle digestion method." 
 
Monika Dzieciatkowska, Ph.D.
Colorado University
Proteomics Core Manager

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800-615-0418 / info@ceresnano.com

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