Virus Capture Kits
Get more from your samples. Knowing a virus is present in a sample and not being able to detect it is frustrating. Use the Nanotrap® Virus Capture Kit to concentrate viruses from complex biological matrices in order to have high quality input material for your downstream analytical methods.
Working with SARS-CoV-2? Click here to learn how Nanotrap particles can help
PRODUCT DESCRIPTION
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Nanotrap® Virus Capture Kit improves the performance of your downstream analytical methods (e.g., PCR, Western blot, NGS, protein assays, infectivity assays) by capturing and concentrating whole virus from complex biological samples.
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Demonstrated to work with influenza, RSV, coronavirus, Zika virus, Dengue virus, and Chikungunya virus.
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Compatible with multiple nucleic acid extraction kits.
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Eliminate false negatives. Nanotrap® particles enabled the identification of SARS-CoV-2 RNA in 9 out of 32 diagnostic remnant samples that had previously tested negative for the virus.
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Nanotrap® particles can enable testing of pooled patient samples by improving the real-time RT-PCR signal from pooled sample volumes up to 10 mL.
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Increase assay sensitivity by capturing and concentrating low abundance viruses. Nanotrap® particles improved the real-time RT-PCR signal in low viral load diagnostic remnant samples by an average of 3.1 Ct values.
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Nanotrap® particles utilize affinity capture and enrichment to attract and bind low abundance viruses. Nanotrap® particles do not utilize antibodies or other biomolecules as affinity molecules.
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Nanotrap® particles triple the nucleic acid yield as compared to QIAGEN column only.
Incorporating the Nanotrap® technology into your workflow is simple. No more than 4 steps added to your current workflow, if you want to keep using your nucleic acid extraction kit.
Or reduce your sample real-time RT-PCR sample processing time by 2-3 fold by eliminating a commercial extraction kit altogether.
Nanotrap® particle technology can enhance other sample preparation products to improve downstream analytical performance. The following data highlight the improvement in viral RNA isolation for flu A detection via RT-PCR using the Nanotrap® Virus Capture Kit.
Reaching the lower limit of detection for an assay can be challenging within a large dynamic range. This kit provides a reproducible method for improving assay sensitivity you need for your assay. In 2 mL spiked transport media samples, the Nanotrap technology significantly improved the nucleic acid yield of a commercially available extraction kit, taking the detectable amount of Influenza A down to less than 1 copy/µL.
low abundance virus
Let the Nanotrap® technology concentrate virus from larger volumes without disrupting your assay’s sample input volume requirement. An array of sample input volumes for influenza A concentrations across four sample volumes processed using the Nanotrap® Virus Capture Kit are shown in comparison with the 150 µL QIAGEN column input volume.
