Virus Capture Kits

Get more from your samples and get it faster.  Knowing a virus is present in a sample and not being able to detect it is frustrating. Use Nanotrap® Magnetic Virus Particles to concentrate viruses rapidly from complex biological matrices in order to have high quality input material for your downstream analytical methods.

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   PRODUCT DESCRIPTION

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• Nanotrap® Magnetic Virus Particles demonstrated to capture and concentrate the following viruses: influenza A H1N1 (1), influenza A H3N2 (1), influenza B (1), respiratory syncytial virus A2001/3-12 (1), coronavirus 229E (1), coronavirus OC43 (2), SARS-CoV-2 (3)(4), Zika (10), and chikungunya (10).

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• Methods developed for clinical swab samples, saliva, and wastewater. (3)(4)(7)(8)

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• Reduce clinical sample processing time by 2- to 3-fold by eliminating commercial extraction kit. 

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• Enables an automated method for concentrating and processing virus from 24 wastewater samples in 40 minutes, reducing processing time by at least 20-fold, as compared to other methods. (8)

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• Enables pooled patient sample testing with methods developed for sample volumes up to 10 mL. (4)(6)

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• Eliminate false negatives. Nanotrap® particles enabled the identification of SARS-CoV-2 RNA in 9 out of 32 diagnostic remnant samples that had previously tested negative for the virus. (4)

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• Increase assay sensitivity by capturing and concentrating low abundance viruses. Nanotrap® particles improved the real-time RT-PCR signal in low viral load diagnostic remnant samples by an average of 3.1 Ct values. (4)

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• Successfully utilized in RT-PCR assays with FDA Emergency Used Authorization for COVID-19. (9)(11)

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• Nanotrap® particles utilize affinity capture and enrichment to attract and bind low abundance viruses. Nanotrap® particles do not utilize antibodies or other biomolecules as affinity molecules.​

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Citations:

(1)   https://www.ceresnano.com/post/respiratory-pathogen-detection

(2)   https://www.ceresnano.com/post/app-note-capture-and-concentration-of-coronavirus-oc43

(3)   https://www.ceresnano.com/post/app-note-capture-and-concentration-of-sars-cov-2-from-viral-transport-medium

(4)   https://www.nature.com/articles/s41598-020-78771-8

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(8)  

(9)  

(10) 

(11) 

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Incorporating the Nanotrap® technology into your workflow is simple. ​Reduce your sample real-time RT-PCR sample processing time by 2-3 fold by eliminating a commercial extraction kit altogether.

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