using nanoparticle entrapment and mass spectrometry Presented at ASTMH 2018 Team detected parasite proteins Method also detected previously unrecognized proteins from multiple tick borne pathogens in urine samples Attributes of the technology include: 1) Rapid harvest of analytes, protection from degradation, and exclusion of unwanted high abundance host proteins; 2) Presence of unique chemical baits immobilized

RT-qPCR targeting the nucleocapsid protein was used for detecting SARS-CoV-2 RNA.

by affinity hydrogel particles (analytical sensitivity = 2.5 pg/mL) to study tick pathogen-specific proteins Specificity was defined by 100% amino acid sequence identity with tick-borne pathogen proteins, evolutionary

is believed that the over-amplification of inflammatory pathways, along with release of toxic viral proteins

AIDS: December 1, 2019 - Volume 33 Objective: The aim of this study was to measure the protein concentration Tat protein and viral RNA were quantified from exosomes isolated from CSF, followed by western blot or Results: Tat protein was detected in 36.8% of CSF samples from HIV-positive patients. Similarly, exosomes from 34.4% of CSF samples were strongly positive for Tat protein and/or TAR RNA.

with a variety of chemical affinity baits to enable broad-spectrum collection and retention of target proteins silico docking predictions support that the affinity between reactive red 120 and ZIKV or CHIKV envelope proteins

shown that the small membrane structures, known as Extracellular Vesicles (EVs), may contain the HTLV-1 protein Here, we show that ionizing radiation (IR) caused an increase in both intracellular Tax protein and HTLV EVs separated by a density gradient show that lower density EVs are positive for gp61+++/Tax+++/HBZ+ proteins

Recently, studies have demonstrated the presence of EBOV proteins VP40, glycoprotein (GP), and nucleoprotein EVs containing EBOV proteins have been shown to induce apoptosis in recipient immune cells, as well as

We sought to understand if this is the case in HTLV-1 infection, and specifically if HTLV-1 proteins Conclusion: Cumulatively, these results show that there are HTLV-1 proteins present in exosomes found

We discovered that upon inhibiting each of the proteins involved in the PI3K/AKT/mTOR pathway, HIV-1

We investigated the effect of cART (RT and protease inhibitors) on the content of extracellular vesicles

Peptides from GRA1, GRA12, ROP4, ROP5, SAG1, and SAG2A proteins were detected by PRM after nanoparticle