Balancing Depth, Reproducibility, and Cost Efficiency in Plasma Proteomics

Tech Note -- Balancing Depth, Redroducibility, and Cost Efficiency in Pasma Proteomics - P.

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Quantitative and discovery plasma proteomics requires workflows that maximize protein identifications while minimizing variability and cost. The Nanotrap® Protein Enrichment Affinity Discovery Kit (Nanotrap® Discovery Kit) delivers highly reproducible, deep proteome coverage while reducing per-sample cost compared to other enrichment kits.

In This Experiment

We evaluated whether the manual Nanotrap Discovery Kit enhances proteome coverage and depth while improving workflow reproducibility in human plasma samples compared to two alternative commercial enrichment kits and unenriched plasma using a standard digestion workflow and Bruker timsTOF HT (dia-PASEF®) analysis.  

TECH NOTE SKU # 34XXX

Lit. # PL-TN31481