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Literature


Effect of nucleic acid concentration method on Severe Acute Respiratory Syndrome Coronavirus 2 detection sensitivity in aircraft wastewater
Article Link Abstract: Global interconnectedness and rapid urbanization intensify the spread of infectious diseases, underscoring the critical need for effective and scalable surveillance. Wastewater-based epidemiology (WBE) has proven to be a practical and cost-effective approach for monitoring community-level pathogen prevalence, such as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Despite WBE's success in municipal settings, its application to aircraft was
Apr 6


Rapid identification of COVID wastewater surges in the absence of case data
Article Link Abstract: Genetic testing of community wastewater (wastewater surveillance) is a valuable tool for following trends in the abundance of SARS-CoV-2 and other infectious disease pathogens over time. Wastewater surveillance is increasingly important in the absence of corresponding epidemiological data, particularly for infectious diseases with limited timely data on clinical case incidences. Due to the inherent noise in wastewater data, a single sample is not suffic
Apr 2


A Sample-to-Results Workflow for RSV Sequencing from Wastewater
This application note outlines a scalable and automation-friendly workflow for respiratory syncytial virus (RSV) surveillance from wastewater, utilizing Ceres' Nanotrap® Microbiome A Particles for viral enrichment, New England Biolabs' Monarch® Mag Viral DNA/RNA Extraction Kit with DNase treatment to reduce gDNA contamination, and NEBNext® targeted sequencing for high genome coverage and accurate strain identification. The workflow addresses challenges of low viral loads an
Apr 2


Capture and Detection of Mycobacterium from Sputum Samples using Nanotrap Microbiome B Particles
Tuberculosis (TB) remains a leading global health concern, causing approximately 1.4 million deaths annually.(1) Early and accurate detection of Mycobacterium tuberculosis in complex clinical samples, such as sputum, is critical for effective diagnosis and treatment. Traditional culture methods, while highly specific, are slow and labor-intensive. Molecular approaches such as qPCR and sequencing provide faster results but are often hindered by inefficient mycobacterial recove
Mar 12


Real-time Public Health Interventions Driven by Wastewater and Environmental Surveillance During Uganda’s 2025 Martyrs Day Mass Gathering
Mass gatherings increase the risk of infectious disease transmission, particularly when healthcare systems are overstretched and underfunded. Wastewater and environmental surveillance (WES) offer a real-time, non-invasive method for monitoring pathogen circulation at the population level. During Uganda’s 2025 Martyrs’ Day pilgrimage, which drew over three million people, the Ministry of Health used WES to identify and respond to health threats.
Feb 18