Evaluating Saturation and Competitive Binding Effects in Nanotrap Microbiome Particles

Poster -- Evaluating Saturation and Competitive Binding Effects in Nanotrap Microbiome Par.

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Nanotrap® Microbiome Particles are an affinity-bait-based capture system with afinite binding capacity. In complex matrices such as wastewater, the binding is also dependent on the sample matrix, and recovery does not scale uniformly with increasing affinity baits on Nanotrap Particle surfaces.¹ Binding analyses with protein analytes have shown complex changes in recovery based on target accessibility and interaction dynamics with hydrogel particles, rather than simple saturation dynamics.¹ 

In this study, the interplay of different spikedin organisms was analyzed to determine the effect of varying concentrations of microbes on the detection of other microbial targets within a wastewater matrix. The effect of different background viral and bacterial concentrations were analyzed for patterns that show a bias associated with microbial concentrations.

POSTER SKU 44XXX

Literature # WW-PO31518