The Ceres PEAK platform represents a cost-effective complementary or alternative for plasma or VDBS proteomic analysis, and can be implemented as an optimized 2 hr plate-based single-day workflow. Inter-day validation confirms its robust reproducibility and strong cross-matrix correlation. Biological validation in ADRD samples confirms 25/31 AD-relevant biomarkers and pathway-level signal from VDBS — establishing a scalable, high-throughput platform for clinical proteomics.

Through the Nanotrap Microbiome A Particle workflow paired with downstream TAC analysis, we aim to demonstrate concentration across a wide range of infectious pathogen targets from wastewater samples gathered in various locations in Dhaka, Bangladesh.

Detection and isolation of intact bacteria from clinical specimens such as whole blood and urine are critical for clinical microbiology and translational research. However, complex matrix effects, low microbial burden, and the absence of sample preparation workflows that enable intact bacterial capture limit downstream analysis.

Evaluation of the Nanotrap PEAK Discovery Method, which uses magnetic hydrogel particles to enrich low abundance proteins from biofluids while depleting high-abundance interferents

Evaluation of Nanotrap® Protein Enrichment Affinity Kit (Nanotrap® PEAK) as a universal protein enrichment solution across multiple blood collection formats—including K2EDTA, K3EDTA, sodium citrate (NaCit), and hemolyzed samples—as well as non-human plasma from mouse and canine sources. The results highlight the flexibility of Nanotrap PEAK to support consistent protein enrichment across diverse matrices—helping enable more robust and scalable proteomics workflows.

Evaluation of 10 μL Nanotrap® PEAK Discovery Method against the standard 50 μL workflow on matched K2EDTA plasma samples.