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Nanotrap PEAK: A Versatile Product for Protein Enrichment From Multiple Sample Types

Updated: Aug 5



Mass spectrometry-based proteomic analysis of plasma is a vital tool for biomarker discovery, yet it is hindered by high-abundance proteins, which can obscure the detection of low-abundance biomarkers. Nanotrap® Protein Enrichment Affinity Kit (PEAK) is a simple, versatile, and easy-to-use kit that improves the detection of low-abundance proteins from multiple sample types. These kits utilize the Nanotrap® magnetic hydrogel particle technology to enrich low-abundance proteins from complex sample matrices.


In this study, three different Nanotrap® Protein Particle types and multiple particle combinations for plasma processing were evaluated. Each of the workflows offers unique benefits, allowing researchers to tailor their approach. Additionally, we investigated whether a simple 30-minute enrichment step using Nanotrap® PEAK would enhance protein identification in plasma, cerebrospinal fluid (CSF), and urine samples.


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SKU # 34XXX

Literature # PL-PO31442


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