This application note outlines a scalable and automation-friendly workflow for respiratory syncytial virus (RSV) surveillance from wastewater, utilizing Ceres' Nanotrap® Microbiome A Particles for viral enrichment, New England Biolabs' Monarch® Mag Viral DNA/RNA Extraction Kit with DNase treatment to reduce gDNA contamination, and NEBNext® targeted sequencing for high genome coverage and accurate strain identification. ​ The workflow addresses challenges of low viral loads an

One of the challenges of working with cell-free DNA (cfDNA) is its small size. cfDNA fragments tend to be 167 bp or multiples thereof, and traditional bead-based DNA extraction methods are less efficient at capturing small-size DNA. Traditional DNA extraction methods have a lower fragment size cutoff of ~50 bp, and the yield is typically lower as the fragment size gets closer to 50 bp. This study will compare the recovery of different extraction methods in this size range and

In this study, the Nanotrap® Protein Enrichment Affinity Kit (PEAK) was compared to a magnetic, protein-binding bead-based enrichment...

The violin plot outlines the run-to-run reproducibility (%CV) of identified proteins among six biological replicates, with the analysis focused on proteins detected in at least three of the six replicates.

Monitoring antimicrobial resistance (AMR) genes in agricultural environments is important for understanding and curbing the spread of...