Wastewater-based Epidemiology
Nanotrap® Microbiome Particles rapidly concentrate microbes from raw sewage, requiring no filtration, centrifugation, or bead-beating.
Large-scale wastewater surveillance is used to help communities monitor infection dynamics for viruses like SARS-CoV-2, bacteria, fungi, and parasites. Nanotrap Particle Technology is used by labs around the world to capture and concentrate important pathogens of interest.
A method using Nanotrap Microbiome A Particles was shown to detect 1 asymptomatic individual in a building of 415 residents and enabled early detection of nearly 85% of individual COVID-19 cases on a university campus.
Wastewater-based epidemiology workflow
Simplified workflow
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Eliminate filtration, centrifugation and bead beating methods, without sacrificing sensitivity.
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Spend less time in the fume hood.
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Shelf stable product for up to 6 years at room temperature — no need for cold storage.
Highly compatible
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Compatible with RT-qPCR, RT-ddPCR, RT-dPCR, and sequencing-based analysis methods.
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Manual and automated protocols available for use with a wide range of RNA extraction kits.
Get better data
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Improved capture efficiency with 2-10x higher recovery.
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Need greater performance? Add a Nanotrap Enhancement Reagent to improve results by another 1-2 Ct values.
Environmentally friendly
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Reduce biohazard waste
by using less plastic consumables compared
to other methods. -
Free up valuable lab storage space.
Supported by the U.S. National Institutes of Health.
Webinars and Interviews
Webinars
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LabRoots Webinar: Wastewater Surveillance: Expanding Microbes of Interest Monitoring Beyond SARS-CoV-2
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Labroots Webinar: Deploying SARS-CoV-2 wastewater monitoring in Kansas. A case study and adoption of high-throughput, automated sample processing
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MACHEREY-NAGEL Webinar: Case Studies in Wastewater Surveillance - Successful Testing Methods in Practice
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Labroots Webinar: Sample collection and concentration methods -- impact on wastewater-based surveillance for multi-pathogen panels
Helpful workflow videos
Interviews
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Interview with Nevada State Public Health Laboratory: How Nanotrap® Particle Technology is Improving the Public Health Response to SARS-CoV-2
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Interview with University of Massachusetts, Amherst: How Nanotrap® Technology for Wastewater Surveillance Improves SARS-CoV-2 Workflows
Poster & applications related to wastewater-based epidemiology testing
Application Notes
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Capture and Concentrate Microbes that Cause Sexually Transmitted Infections from Wastewater
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Capture and Concentrate Pathogenic Legionella Species from Environmental Water Samples
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Nanotrap Microbiome A and B Particles can be combined to improve microbe capture from wastewater
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Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission
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Comparison of Nanotrap Microbiome A Particles, membrane filtration, and skim milk workflows for SARS-CoV-2 concentration in wastewater
Customer Advances
Delaware Public Health Lab
Read how the team at the Delaware Public Health Lab is using Nanotrap Technology to improve recovery, and expand their targets.
West Virginia University - Environmental Water Surveillance
Read how the team at West Virginia University is using Nanotrap Technology to get more accurate samples, have faster turnaround time, and reduce PCR contaminants and sample inhibition.