Use of Nanotrap® particles for capture and enrichment of febrile-illness-causing pathogens including Zika, Chikungunya, Dengue and Influenza viruses
Presented at ASM CVS 2018
We assessed the utility of Nanotrap® particles for capture and enrichment of febrile-illness causing pathogens, including Zika (ZIKV), chikungunya (CHIKV), dengue (DENV) and influenza (FLU) viruses. Through use of qRT-PCR methods, we have demonstrated that Nanotrap® particle type CN1030 provides at least 8-fold enrichment of ZIKV, CHIKV and DENV from urine biospecimens. We demonstrated detection of ZIKV, CHIKV and DENV at viral concentrations as low as 0.1 PFU/mL.