App Note: Rapid SARS-CoV-2 Viral Isolation from Wastewater


APPLICATION NOTE SKU 44XXX


Download full application note here


Key Advantages


> Nanotrap® Magnetic Virus Particles concentrate SARS-CoV-2 wastewater sample with no centrifugation or filtration.


Introduction


According to the Centers for Disease Control and Prevention, SARS-CoV-2 can be shed in the feces of individuals with asymptomatic or symptomatic infections, making SARS-CoV-2 RNA detection in sewage a COVID-19 indicator that is independent of healthcare-seeking behaviors and access to clinical testing.1 Due to low concentrations in water samples such as sewage, SARS-CoV-2 viral particles must be concentrated prior to nucleic acid isolation. The three most common approaches for viral particle concentration are filtration and concentration using electronegative membranes, ultrafiltration, and precipitation. These approaches are time consuming and cumbersome, requiring access to complex laboratory equipment like centrifuges, which limits the daily sample throughput. 2-5


Here we describe a simple and rapid approach, using Nanotrap® Magnetic Virus Particles to capture and concentrate SARS-CoV2 from wastewater samples prior to nucleic acid isolation. Because it requires no filtration or centrifugation steps, this approach is amenable to high throughput implementation.



Recent Posts

See All
  • LinkedIn Classic
  • Twitter App Icon
  • Facebook Social Icon

9460 Innovation Drive, Manassas, VA, 20110, United States

800-615-0418 / info@ceresnano.com

© 2020 Ceres Nanosciences, Inc. All Rights Reserved